Altered esterase activity due to pesticide exposure in the aquatic snail Physa acuta.

Maredza, Alice (2013) Altered esterase activity due to pesticide exposure in the aquatic snail Physa acuta.

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Official URL: http://ir.nust.ac.zw/xmlui/handle/123456789/315

Abstract

The effect of pesticides on the xenobiotic metabolising enzymes of the aquatic snail Physa acuta was studied. Adult snails reared in the laboratory were exposed daily for three days to the following pesticides: 2,4-dichlorophenoxyacetic acid, deltamethrin, endosulphan,malathion and pirimiphos-methyl, Cytosolic fractions prepared from the snails showed that pesticide exposure had no effect on the glutathione or glutathione dependent enzyme activities. General esterase activity using two different substrates was reduced significantly by exposure to the organophosphate pesticides malathion and pirimiphos. Exposure to the other pesticides did not cause any substantial changes in the esterases activities. The nature of this inhibition is not yet apparent. It is likely, however, that the changes are due to a competitive type inhibition by the pesticides for the active site of the enzyme.,International Foundation for Science, Stockholm, Sweden (No Al2036) Research Board, University of Zimbabwe and the International Program in the Chemical Sciences, Uppsala University, Sweden.

Item Type: Article
Uncontrolled Keywords: Esterases,Aquatic snail Physa acuta,Pesticide
Divisions: Universities > State Universities > National University of Science and Technology
Depositing User: Mr. Edmore Sibanda
Date Deposited: 30 Nov 2015 23:00
Last Modified: 30 Nov 2015 23:00
URI: http://researchdatabase.ac.zw/id/eprint/1114

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