Yellow maize with high B-carotene is an effective source of vitamin A in healthy Zimbabwean men.

Muzhingi, Tawanda (2011) Yellow maize with high B-carotene is an effective source of vitamin A in healthy Zimbabwean men.

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Official URL: http://ir.nust.ac.zw/xmlui/handle/123456789/220

Abstract

Background: The bioconversion ef?ciency of yellow maizeb-carotene to retinol in humans is unknown.Objective: The objective of this study was to determine the vitamin. A value of yellow maizeb-carotene in humans. Design: Highb-carotene?containing yellow maize was grown in a hydroponic medium with 23 atom% 2H2O during grain development. Yellow maizeb-carotene showed the highest abundance of enrichment as [ 2H 9]b-carotene. Eight healthy Zimbabwean men volunteered for the study. On day 1 after a fasting blood draw, subjects consumed 300 g yellow maize porridge containing 1.2 mg b-carotene, 20 g butter, and a 0.5-g corn oil capsule. Onday 8, fasting blood was drawn, and subjects consumed 1 mg [13C10]retinyl acetate in a 0.5-g corn oil capsule and 300 g white maize porridge with 20 g butter. Thirty-six blood samples were collected from each subject over 36 d. Concentrations and enrichments of retinol andb-carotene in labeled doses and serum were determined with the use of HPLC, gas chromatography?mass spectrometry, and liquid chromatography? mass spectrometry. Results: The area under the curve (AUC) of retinol from 1.2 mg yellow maizeb-carotene was 72.9 nmol ? d, and the AUC of retinol from 1 mg retinyl acetate 13C10 was 161.1 nmol? d. The conversion factor of yellow maizeb-carotene to retinol by weight was 3.26 1.5 to 1. Conclusion: In 8 healthy Zimbabwean men, 300 g cooked yellow maize containing 1.2 mgb-carotene that was consumed with 20.5 g fat showed the same vitamin A activity as 0.38 mg retinol and provided 40?50% of the adult vitamin A Recommended Dietary Allowance.

Item Type: Article
Uncontrolled Keywords: B-carotene,Zimbabwean men,Yellow maize
Divisions: Universities > State Universities > National University of Science and Technology
Depositing User: Mr. Edmore Sibanda
Date Deposited: 01 Dec 2015 01:01
Last Modified: 01 Dec 2015 01:01
URI: http://researchdatabase.ac.zw/id/eprint/1228

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