Hepatic Cytosolic Glutathione S- Transferases of ostrich (struthio camelus): partial characterisation and interaction with xenobiotics.

Naik, Yogeshkumar S. (2015) Hepatic Cytosolic Glutathione S- Transferases of ostrich (struthio camelus): partial characterisation and interaction with xenobiotics.

Full text not available from this repository.
Official URL: http://ir.nust.ac.zw/xmlui/handle/123456789/497

Abstract

An article with pictures.,The glutathione S-transferases (GSTs) in affinity purified pools of male and female ostrich liver were studied. The GSTs were purified from crude liver cytosols by S-hexylglutathione sepharose affinity chromatography with yields comparable to those reported for GST from mammalian livers. The K, for both glutathione (GSH) and 1-chloro-2,4-dinitroSenzenzene (CDNB) were determined and found to be within the range of values known for mammalian and invertebrate species. 1- chloro-2,4-dinitrobenzene proved to be the best of nine substrates tested to measure activity. Activity was inhibited by bromosulphophthalein and cibacron blue which are well known inhibitors of the mammalian enzyme. Our results indicate that the ostrich liver enzymes behave similarly to the mammalian liver enzyme in terms of substrate requirements and inhibition characteristics.,Zimbank

Item Type: Article
Uncontrolled Keywords: Hepatic cytosolic,Glutathione S-transferases,ostrich,xenobiotics
Divisions: Universities > State Universities > National University of Science and Technology
Depositing User: Mr. Edmore Sibanda
Date Deposited: 01 Dec 2015 01:02
Last Modified: 01 Dec 2015 01:02
URI: http://researchdatabase.ac.zw/id/eprint/1247

Actions (login required)

View Item View Item