Epidemiological consequences of non-compliance to HCV therapy among IDUS

Mushayabasa, S. (2011) Epidemiological consequences of non-compliance to HCV therapy among IDUS.

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Official URL: http://ir.nust.ac.zw/xmlui/handle/123456789/216


Treatment for infections with hepatitis C viruses has recently developed markedly, and range from nonspecific interferon-based treatments to specific antiviral treatments, such as those that inhibit hepatitis virus coded protein production or activity. Despite advancements in the management of HCV, the epidemic prevalence continues to rise among injection drug misusers who, are responsible for approximately 90% of new HCV cases, because of their poor compliance with treatment requirements and conditions. A simple mathematical model is developed to explore the impact of treatment defaulting on the transimission dynamics of HCV among injection drug misusers. Numerical simulations are provided to support analytical findings.

Item Type: Article
Uncontrolled Keywords: HCV therapy,IDUS,non-compliance,reproductive number,sensitivity analysis
Divisions: Universities > State Universities > National University of Science and Technology
Depositing User: Mr. Edmore Sibanda
Date Deposited: 01 Dec 2015 02:02
Last Modified: 01 Dec 2015 02:02
URI: http://researchdatabase.ac.zw/id/eprint/1291

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