Assessing the effects of drug use on the transmission dynamics of HIV/AIDS

Bhunu, C.P. (2011) Assessing the effects of drug use on the transmission dynamics of HIV/AIDS.

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Research article.,Drug misuse has been recognized to have a significant impact on the spread of HIV/AIDS epidemic. A deterministic model to theoretically assess the contribution of drug misuse to the spread of HIV/AIDS is investigated. The basic reproduction number of the model is determined and stability of equilibria analysed. The disease free equilibrium point is shown to be globally asymptotically stable when its corresponding basic reproduction number is less than unity. The Centre Manifold theory is used to show that the endemic equilibrium point is locally asymptotically stable when its corresponding reproduction number is greater than unity. The results obtained from the analysis of the basic reproduction number show that drug use increases the basic reproduction number. This suggests that drug misuse has the potential to fuel the epidemic. Results from numerical simulations show that HIV infected drug abusing individuals progress to the AIDS stage and die at a faster rate than their corresponding HIV infected parts.

Item Type: Article
Uncontrolled Keywords: Drug use,Transmission dynamics,H.I.V/AIDS
Divisions: Universities > State Universities > National University of Science and Technology
Depositing User: Mr. Edmore Sibanda
Date Deposited: 01 Dec 2015 02:02
Last Modified: 01 Dec 2015 02:02

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