Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age.

Mutapi, Francisca and Winborn, Georgina and Midzi, Nicholas and Taylor, Matthew and Mduluza, Takafira and Maizels, Rick M (2007) Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age. p. 139. ISSN 1471-2334

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Abstract

Taken together, these results show that the IL-10 responses develop early compared to the IL-5 response and may be down-modulating immunopathological responses that occur during the early phase of infection. The results further support current suggestions that the Th1/Th2 dichotomy does not sufficiently explain susceptibility or resistance to schistosome infection.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RB Pathology
R Medicine > RC Internal medicine
Depositing User: Professor Takafira MDULUZA
Date Deposited: 11 Apr 2012 12:07
Last Modified: 11 Apr 2012 12:07
URI: http://researchdatabase.ac.zw/id/eprint/148

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