Changes in the humoral immune responses after chemotherapy in single and co-infected individuals with Schisosoma haematobium and Plasmodium falciparum.

Zinyowera, S and Muchaneta-Kubara, C E and Mutapi, F and Midzi, N and Ndlovu, P D and Mduluza, Takafira Changes in the humoral immune responses after chemotherapy in single and co-infected individuals with Schisosoma haematobium and Plasmodium falciparum. pp. 104-11. ISSN 0008-9176

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Abstract

Schistosomiasis is a problem in rural settings as in all the four schools > 50% of the pupils were infected, whilst those that were < 15 years of age had high egg intensities. There was a rise in sera IgE antibodies against SEA and CERCA in all the cases that were treated with praziquantel, an indication that treatment does alter the immune response favouring resistance to infection by Schistosoma haematobium. Those that had malaria singly or coinfected produced high levels of sera IgE against SEA an indication that malaria infection influences the cytokine environment to favour production of IgE isotypes against the schistosome egg antigen.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RB Pathology
Depositing User: Professor Takafira MDULUZA
Date Deposited: 11 Apr 2012 12:06
Last Modified: 11 Apr 2012 12:06
URI: http://researchdatabase.ac.zw/id/eprint/153

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