National Research Database of Zimbabwe

Ultrasonographic organometry: liver and spleen dimensions among children in Zimbabwe.

Friis, H and Ndhlovu, P and Mduluza, T and Kaondera, K and Franke, D and Vennervald, B J and Christensen, N O and Doehring, E (1996) Ultrasonographic organometry: liver and spleen dimensions among children in Zimbabwe. pp. 183-90. ISSN 1360-2276

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Attempts have been made to develop a staging system of sonographic Schistosoma mansoni morbidity for use in epidemiological studies and for evaluation of control programmes. Therefore, normal dimensions of livers and spleens in children in countries with endemic S. mansoni infections need to be established. Normal dimensions of livers and spleens are presented, based on examination of 144 Zimbabwean children between 8 and 16 years of age found to be S. mansoni egg negative 12 months after treatment with praziquantel. Based on the liver and spleen measurements, an index of liver size and the spleen volume were calculated. Height was employed as the independent variable in all multiple regression models. The organometric data are presented as prediction plots, with observed values and fitted regression line with 95% confidence and prediction intervals. The mean spleen volume was 30% larger for boys than for girls, whereas there was no consistent difference in liver size. No effect of growth Z-scores was seen. The measurements were compared with normal dimensions of livers of German children. For a given height, the mean index of liver size was lower in Zimbabwean than in German children, but inter-observer variation could be a possible explanation for this difference.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
Depositing User: Professor Takafira MDULUZA
Date Deposited: 19 Mar 2012 08:36
Last Modified: 19 Mar 2012 08:36

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